*’Nano’ means….
Nanometer: one billionth of a meter
Nano-: prefix comes from the Greek word for ‘dwarf’
Chemical, physical, and biological properties that differ from those of their larger, or bulk counterparts
Nanotechnology: The National Nanotechnology Initiative(NNI)-> the science of materials and phenomena in the range of 1 to 100nm in diameter
*Features of ‘nanoparticles
Ⅰ. 자폐아의 발달적 접근
아동을 다루는 임상가들은, 아동의 정신병리적 행동에 대해 자문을 구해오면 제일 먼저 아동의 나이를 묻는다. 똑같은 행동이라도 아동의 나이에 따라 정상행동인지 아닌지를 결정한다. 이와 같이 아동기의 정신병리적인 행동은 발달의 맥락에서 언제 그 행동이 일어났는지
1. Introduction of NVP-BEZ235
NVP-BEZ235 소개
Novartis
스위스 바젤에 본사를 두고있는 다국적 제약회사로 세계
각지에서 연구소를 운영중
1996년, 스위스에서 가장 큰 두 개의 제약·의료업체인
시바 가이기(Ciba-Geigy)와 산도즈(Sandoz)의 합병을
통해 설립
2010년 기준 총 매출액 세계 2위(506억 US $)
2010년
3 methods in Phase 1
Standard Method
Rule-based design
proceeds with
cohorts of three
patients.
If one of the first
three patients
experiences toxicity, three more patients will be treated.
Continual Reassessment Method(CRM)
All patients are
treated maximum tolerated dose.
(MTD)
The original CRM allowed for multiple dose escalations and de-escalations.
Accelerated
Titra
increase.
If this situation is continued, account of health insurance will have a deficit.
Korean use seventy or eighty millions of money as medical cost all their life and half of their medical cost is used after 65-years-old.
Korea face an aging-society, so economic action of man in the prime of life is very important. Therefore, we need countermeasures about increasing medical cost.
in task.
5. Skills
As Celltrion is a pharmaceutical company, its main purpose is developing and manufacturing bio-medicine. In that area, the no.1 skill which Celltrion has is ‘bio-similar’. Bio-similar is a variant of a biopharmaceutical that is marketed following the expiry of the original patent. It means that bio-similar copied original medicine’s quality, effect and safety. Also as
- Marijuana consists of the dried and crushed leaves and flowering tops of the hemp plant, Cannabis sativa. It is most often smoked, but it may be chewed, prepared as a tea, or eaten in baked goods.
- At first, it was marketed by several drug companies as a treatment for rheumatism, gout, depression, cholera, and neuralgia. It was also smoked for pleasure.
- Psychological effec
지질혼합물
피부 각질층 성분과 유사
대부분 oil-in-water emulsion
AD (Atopic Dermatitis)
Ceramide 부족이 원인
Objective
An Open clinical crossover evaluation was conducted to investigate the effects in Atopic Dermatitis(AD) of a multi-lamellar emulsion(MLE) that contained pseudoceramide(PS-9S). - Control group : CMC (Commercial moisturizing cream : 5% urea)