Clozapine ?
Clozapine : antipsychotic drug
최초의 비전형적(Atypical) 항정신병 약물
추체외로 증후군 (Extrapyramidal symptoms) X
항 정신병 약물의 대표 부작용
운동능력 소실 등
변연계 도파민 수용체에 특이적
Mechanism of action
아드레날린성, 세로토닌성, 히스타민성 및 콜린성 수용체 등에 길항
Pharmacokinetics (AD
I. What is drug
When an individual persists in use of alcohol or other drugs despite problems related to use of the substance, substance dependence may be diagnosed. Compulsive and repetitive use may result in tolerance to the effect of the drug and withdrawal symptoms when use is reduced or stopped. This, along with Substance Abuse is considered Substance Use Disorders.
II. Varieties of
(1)-1. Drug pricing system and drug market characteristics
The drug repayment price in health insurance is determined by the Japanese ministry of labor welfare.
The labor welfare ministry periodically investigates market price of pro drug products in order to include the actual-trading price into the drug pricing method.
The insurance drug pricing system of Japan
prescribed morphine...
a drug suitable for angina, but not at all suitable for emphysema...
which is unfortunately what the old man actually had.
Within an hour, the patient became unresponsive and diaphoretic...
and was raced up to Intensive Care, with an irregular pulse of ...
blood pressure over respiration rapid and shallow.
The resident on duty in Intensive Care compounded the blunder...
by
prescribing and dispensing drugs.
receiving prescription at hospital
getting medicines at pharmacy.
▶ Most of hospitals have their own pharmacy
in entrance or inside of hospital.
3) Medical insurance
▶ Person pay 20% of total medical payment in hospital.
▶ Medicines payment are insured 100%.
※ Despite these medical insurance existence,
53% of Vietnamese patient