double targeting, we use special peptide pHLIP(pH Low Insertion Peptide). Cancer cells accumulate pyruvate due to insufficient O2 and consequent decrease of oxidative phosphorylation. So H+ pumps transport protons to extracellular fluid to maintain normal cytoplasmic pH.
Thus, Tumor acidity is a specific tumor biomarker. pHLIP is pH-dependent molecule, so it detects the concentration change o
double space)로 작성되어야 하며, 다른 학술논문에도 한 줄 띄어쓰기를 하는 것이 바람직하다. 그러나 안으로 들여 쓴 인용문단(Indented block quotation)은 행간 여백을 주지 않을 수도 있다(single space). 통상 각주, 항목별 목록, 參考文獻 등은 행간 여백을 주지 않되, 각각의 註, 항목, 자료 사이에는 한 줄을 비
@ Showed lesions and narrowing consistent with CHD in 77% of
the soldiers whose average was 22 years.
@ Studying the development and progression of coronary artery lesions in infants and chlidren support the view that atherosclerosis begins in childhood and progresses slowly
Into adulthood.
@Pathobiological Determinants of Atherosclerosis in Youth(PDAY): early atherosclerotic lesions
Abstract—We designed high-throughput microchip which detects single nucleotide polymorphisms (SNPs). The chip consisted of DNA extraction part and SNP detection part. DNA was extracted by lysis buffer, and then amplified by polymerase chain reaction (PCR). In SNP detection part, CEL I endonuclease selectively cleaved mismatched dsDNA, so wild type DNA was distinguished from mutant type. Sig
In the Second World War the Japanese army invaded and subsequently occupied Malaya, Sabah, Sarawak, and Singapore for over three years. During this time, ethnic tensions were raised and nationalism grew. Popular support for independence increased after Malaya was reconquered by Allied Forces. Post-war British plans to unite the administration of Malaya under a single crown colony called the Malay