1) Rivalry among Competing Sellers: Fierce to Strong
(1) Big Three U.S. Companies
Automobile companies are facing vigorous battle in North America, and some companies have to deal with their net loss and huge amount of debt. General Motors Co., Ford Motor Co., and Chrysler Group LLC, so called ‘Big Three’ in automotive industry got through major crisis in 2008, and GM ended up filing
3. 암화에 의한 세포주 확립
동물세포를 이용한 연구 발전에 기여
4. Sato등에 의해 무혈청 배양법 확립
1960. 무혈청 배양 시도
1963-5(Ham) 혈청 공급 없이
CHO cell cloning
1970(Sato) 혈청 대신 호르몬
첨가 cellline 무혈청 배양
성공
Human embryonal kidney, SV40 and large T antigen transformed
1908 - The term "stemcell" was proposed for scientific use by the Russian histologist Alexander Maksimov (1874–1928) at congress of hematologic society in Berlin. It postulated existence of haematopoietic stemcells.
1998 - James Thomson and coworkers derive the first human embryonic stemcellline at the University of Wisconsin–Madison.
2004–2005 - Korean researcher Hwan
stemcells especially.
First of all, we can raise a question on its efficacy. To make this new concept of curing cancer to be
widely available, a high NSC/tumor cell ratio certainly seems to be a crucial problem to be solved in the
near future. For instance, one group transduced a murine NSC line ex vivo to express an enzyme, then
implanted the transduced NSCs along with a rat glioma cell
cell이 pancreatic celllineage line으로 분화될 수 있음을 보여준다.
해당 연구가 진행되었던 배경은 인슐린을 생산하는 섬세포(islet cell)는 신경단위세포(neuron)와 유사하다는 점과 배아 줄기세포(embryonic stemcell)를 인슐린 생산 세포로 변환시킨 선행 연구 사례를 통해 neural progenitor cell을 이용하게 되었다. 또