drug delivery. At the same time, it is also required to retain thedrug stability and ensure that early degradation ofdrugs from the nanocarriers does not take place.
Therefore, fordrugs to be successfully delivered to their target, many factors such as its size, biocompatibility, target specific affinity, avoidance of reticuloendothelial systems, stability in blood, or ability to facilitate
of life is directly related to the targeting ability of treatment, so that method has some side effects.
So finding less toxic agents and choosing a precise delivery system is a task currently important.
Regulation of nanoparticles.
Size : 10~100nm (EPR effect)
Coating PEG polymer
Why nanoparticles?
1) It can deliver a larger quantity ofdrugs with better safety.
2) Easy to attach targe
The major threats to the FedEx business model are the other major competitors within their market segment. For example, BAX Global and DHL are two services that also experienced continued growth in these years. Since those companies have the same majority of services that FedEx does, it would be easy for FedEx competitors to use a competitive advantage such as a proprietary product or service tha
of EPR effect. So size of particles is important.
2. Integrin αvβ3
Integrin αvβ3 is the method for active targeting. Most of cancer cell have these receptor. Selection of molecules which target this receptor should be made.
For our strategy to use double targeting, we use special peptide pHLIP(pH Low Insertion Peptide). Cancer cells accumulate pyruvate due to insufficient O2 and conseq
and folate needs are lower
Water
Food choices: MyPyramid
Practices to avoid while breastfeeding
Alcohol, drugs, smoking, excess caffeine
Growth is the best marker of nutritional status
Evaluated using growth charts
Weight gain
Double birth weight by 4 to 6 months
Triple birth weight by 12 months
Length gain
Increase length by 50% by 12 months
Head circumference
Readiness for solids