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분야
pptCoenzyme Q 10 기능성
Coenzyme Q 10 섭취량
Coenzyme Q 10 효능 및 임상실험
Coenzyme Q 10 제조기준 및 규격
Coenzyme Q 10 시장성
심장펌프능력, 박출율, 운동내성, 확장기 기능부전 등에서 개선
1990년 미국 심장학회지 Anerican Journal of cardiology(AJC)에 개재된 연구결과
심근육 기능부전(Myocdrdical failure)환자 126명이 매일 Q10 복용
→결과: 시험 초기 41%였던 평균 박출율이 3개월 후 71%의 환자들이 박출율 개선된 결과 보임
협심증, 심부전, 부정맥, 승모판 탈출증, 동맥경화에 도움
나이가 들수록 체내 코엔자임 Q10이 감소
항산화능력, 에너지 생산능력 감소로 연결되어 보호기능이 감소
성상 : 고유의 색택과 향미를 가지며 이미,이취가 없어야 함
코엔자임Q10
원료성 제품 : 표시량 이상
최종제품 : 표시량의 80～120%
잔류용매 (해당 용매를 사용한 경우에 한함)
헥산(mg/kg) : 5.0이하
아세톤(mg/kg) : 30.0이하
이소프로필알콜(mg/kg) : 50.0이하
초산에틸(mg/kg) : 50.0이하
식품의약품안전청 홈페이지
논문
식품산업에서의 코엔자임 Q10의 응용가능성/ 서울여자대학교 식품공학과/심은정
Geromel V,Darin N, Chrétien, Bénit, P, DeLolay P, RötgA,Munnich A, Rustin P. CoenzymeQ10 and idebenone in the therapy of respiratory chain diseases: rationale and comparative benefits. MolGenet Metab. 2002;77:21-30
Kitamura N, Otaki M, et al. Myocardial tissue level of coenzyme Q10 in patients with cardiaac failure. In Folkers K, ed. Biomedical and clinical aspects of coenzyme : proceedings of the Internatinal Sympisium on CoenzymeQ. Amersterdam: Elsevier Scientivic, 1984:243- 352
Burke BE, Neuenschwander R, Olson RD. Randomized, double- blind, placebo-controlled trial of coenzyme Q10 in isolated systolic hypertension. South Med J. 2001; 94(11)1112-7
hansen IL, Iwamoto Y, Kishi T, et al. Bioengetics in clinical medicine. IX. Gingival and leukocytic deficiencies of coenzyme Q10 in patients with periodontal disease. Res Commun Chem Pathol Pharmacol 1976;14:729-38
Littaru GP, Nakamura R, Ho L, et al. Deficiency of coenzyme Q10 in gingival tissue from patoents with periodontal disease. Proc NatlAcad Sci U S 1971;68:2332-5
Wilkinson EG, Arnold RM, Folkers K. Bioengetics in clinical medicine, VI. adjunctive treatment of periodontal disease with coenzyme Q10. Res Commun Chem Parmacol 1976;14:715-9
Premkumar VG, Yuvaraj S, Vijayasarathy K, Gangadaran SG, Sachdanandam P. Serum cytokine lovels of interleukin- 1beta,-6,-8, tumour necrosis factor- alpha and vascular endothelial frowth factor in breast cancer patients treated with coenzyme Q10, fiboflavin and niacin. Basic Clin Pharmacol Toxicol.2007;100(6):387-91
Müller T, Büttner T, Gholipour AF, Kuhn W. Coenzyme Q10 supplemetation provides mild symptomatic benefit in patients with parkinson's diease. Neurosck Lett. 2003:341(3)201-4
Balercia G, Mancini Am Paggi F, Tiano L, Pontecorvi A, BoscaroM, Lenzi A, Littarru GP. COENZYME Q10 AND MALE INFERTILITY. J Endocrinol Invest. 2009 May 21.[Epub ahead of print]
