of chronic stress, can cause hippocampal neurons to wither and die in experimental animals. This degeneration ofthe hippocampus sets off a vicious cycle in which the stress response becomes more pronounced, leading to even greater cortisol release and more hippocampal damage. Human brain imaging studies have posttraumatic stress disorder, an anxiety disorder that is triggered by exposure to ines
menstruation normally but suffer from amenorrhea(absence of periods)
in later years
General factors
- thyroid disorders, adrenal disease
- presence of autoimmune antibodies
- heavy alcohol use, drugs, toxins (pesticides and lead), smoking,
medicines, radiation treatment, chemotherapy for cancer, etc.
-smokingreduces the age of menopause
The glucagon receptor is a 62 kDa peptide that is activated by glucagon andis a member ofthe G-protein coupled family of receptors.
Stimulation ofthe receptor results in activation of adenylate cyclase andincreased levels ofintracellular cAMP.
Glucagon receptors are mainly expressed in liver andin kidney with lesser amounts found in heart, adipose tissue, spleen, thymus, adrenal glands, p
that moderate daily coffee consumption does not increase blood pressure inthe long term.
2. Serum Cholesterol
Two substances found in boiled coffee, cafestol and kahweol, have been shown to raise cholesterol levels.
Cafestol suppresses bile acid synthesis.
→ suppression of bile acid synthesis may provide an explanation for the cholesterol-raising effect of cafestol in humans
4. Competitor Assessment
We will compete withthe market in beer and soft drinks.
As there is no fruit flavored beer in Korea, there is no threat of new entrants but there can be existing threat of substitute product such as soft drinks, beers, juice and fruit flavored sodas. But soft drinks, and beverages are really different with beer. Beer is made from malt, and hops and it's naturally fe