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분야
pptx2.Immortalization
3.Application
4.Conclusion
5.References
→ Proliferation Continue
→ Senescence do not occur
Spontaneous immortalizing
Overexpression of Growth activating Gene
Surpression of Growth inactivating Gene
Surpression of Senescence related Gene
By SV40LT Ag
By hTERT
By Bcl-2 family (BAX)
2.Immortalization- Transformation Assay
Assay by overexpression of Oncogenic H-ras gene
Host cell for Virus Vaccine
Produce Human bioactive Material
Nuclear donor cell for Cloning Animal
Study for Cell Senescence & Cancer
Cellular mechanism
Drug screening
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