1.1.2. Cyclooxygenase-prostanoid cascade
Figure 1.1. Metabolism of arachidonic acid
Despite the diverse chemical structure of aspirin-like drugs, the antinociceptive effect of NSAIDs is mainly due totheir common property of inhibiting cyclooxygenases involved in the formation of prostanoids. Prostanoids areformed by most cells and act as autocrine and paracrine lipid mediators. They are n
of the structure dating back to the Joseon Dynasty had vanished in the flames.
Police could examine CCTV footage from cameras near the gate so had been able to identify a suspect entering the structure.
b. Kang Ho-sun Case
"Kang Ho-sun" was convicted of kidnapping and killing eight women between 2006 and 2008, and of burning to death his wife and mother-in-law in 2005. Kang, 38, was arrested
January 6th, 2012, Seo(16) and other 5 highschool students were arrested for bullying their peer student out of North Face jumper to Samsan police station, Incheon. And December 19th, in Busan, 2012 Park(15) and other 5 students dragged Kim(13) off to a nearby alley to take North Face jumper which is about \330,000 and beat Kim(13) that he got injuries requiring four weeks of medical treatment.
of the bank's Barings Futures subsidiary in Singapore.
As losses mounted, on 25 February 1995 he walked away, when he realized that bank was unable to make the cash payments required by the exchanges.
When Nick Leeson realized that his operations came to light he walked away, but he was arrested in March while on a stop-over in Germany.
On December 2, 1995, a Singapore court sentenced him to
of manpower supply and demand
A large change happened to a manpower supply and demand structural labor supply form industrial after the latter half of 1980's. On first, producing job and white-collar worker supply and demand disproportionate is getting.
Arrest difficulty gets worse in case of low-educated people producing jobs, on the other hand, application difficulty is getting worse in c
of development of the country. In this regard, China claims that human rights are being improved. China also repeated many times that its constitution specifies not only citizenship rights but also the "Four Cardinal Principles", in legal respect the "Four Cardinal Principles of Chinese socialism" are higher than citizenship rights, meaning there is legal base when China arrests people who want
STEP1: ABOUT SKIN CANCER
Cause of cancer _ 2 cases
1.Cell growth doesn’t stop
2.Disorder of apoptosis
p53 : Tumor repressor gene
P53 : transcription factor
Functions
-p53 are that first arrest cell cycle so control cell growth, also active apoptosis suicide program
P53 mutation ->p53 sytem breaks down, it can’t act as Transcriptor factor-> generating tumor
break and linear chromosome.
- Mammalian’s telomere compose of
(5'-TTAGGG-3')n.
- Human’s telomere length : 15-20 kb
- Disappearance 50-200 bp/ one duplication
(the end-replication problem).
no more doublings
(No hTERT)
continuous doublings
(+ hTERT)
of keratinocytes on feeder-layers inhibits the
premature growth arrest>
arrest 있어 ICU 입원하여 2/4-2/16 까지 치료받다가 2/16에 상태 호전되어 동관 8층으로 입원. 2/16일 밤 9시에 respiration arrest 와서 다시 3316에 입원함.
6) 과거병력: DM(+), HTN(+), 2006년 7월 1st attack. 2006년 12월 2nd attack 있어 구로 병원에서 치료받음.
7) 가족병력 : 아들-당뇨, 고혈압.
2. 정신적, 정서적 상태
1)
of the world's most famous characters, was a big hit, selling 40.2 million copies. Also this is the generation where Sega released its first console, Sega Master System, in 1986. However, it was merely a threat to Nintendo because units of Famicom sold was 60 millions whereas units of Sega Master System sold was 13 millions.
4th Generation
The fourth generation is known as 16-bit era. The gam